Not surprisingly given his status as Hollywood's heartthrob-in-chief, George Clooney courted some very desirable ladies before deciding to settle down with beautiful British lawyer Amal Alamuddin, whom he will wed in fairytale style in Venice this weekend.
Before the star is off the market for good, take a look at a gallery of his previous plus ones.
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Many of his former girlfriends have gone on to find happiness. Stacy Keibler, for example is happily married and is the mother of a baby girl. Told of the engagement, she said: "I wish him nothing but happiness".
Kelly Preston has been Mrs John Travolta for more than two decades, while Talia Balsam, George's ex-wife, is married to Mad Men's very own silver fox John Slattery.