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  • Francesca Annis and Ralph Fiennes
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    Age difference: 18 years

    Ralph Fiennes met Francesca Annis, nearly two decades his senior, when she played his mother in a London stage production of Hamlet. Sparks flew, and in 1996 the two left their relationships he was wed to ER's Alex Kingston and she was photographer Patrick Wiseman's partner of 22 years to begin a romance. "I think if two people have a strong connection and a strong bond, that's what's important," Ralph says of the age gap. "Certainly in my life, age difference has not been a problem."