The warmth between the two ladies was clear as they stood arm-in-arm on the red carpet at the Amfar event in Italy - Janet in a beautiful midnight blue wrap-around floor-length gown designed for her by Donatella.
Their appearance followed fashionista Janet's front-row seat at Versace's Milan show on Saturday.
It wasn't the first time the Versace designer has created an outfit for the 43-year-old songstress, who recently described Donatella in an interview as a "sweet, nurturing woman."
She was also behind the clothes worn by the whole of the Jackson clan at the memorial for their late brother Michael this summer.
Earlier in the evening, Donatella hosted a dinner party for 150 family and friends, including Janet and her love Jermaine Dupri.
And then it was off to the Amfar do – held in conjuction with fashion week - at which the Got til it's Gone singer acted as a co-host.
Other stars who turned out to show their support for the glamorous auction event included Kanye West – fresh from his controversial outburst at the MTV Awards earlier this month – and Dita Von Teese, who put on a special burlesque performance for invitees.
Canadian beauties Rachel Bilson and model Linda Evangelista were also in attendence.