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The two British actors star as best friends who take a leap of faith as teenagers and decide to go to the US together to attend university. But fate has other plans for Rosie, and Love, Rosie follows the pair over the next 12 years as their lives change dramatically but the connection remains.
In this exclusive clip, teenagers Lily and Alex discuss the terrible events of "last night", as Alex admits to Lily he took the fall for the fact that she ended up in hospital.
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The pair then discuss Alex's crush on local girl Bethany, played by model Suki Waterhouse in one of her first major acting roles.
Will you be watching Love, Rosie, out in cinemas on 22 October? Tweet us @hellomag with the hashtag #LoveRosie