"Anne Hathaway is so nice and everyone who says things like that are bullies and they're mean", said Oscar nominee Jessica.
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She continued: "She's so nice, she's so talented, she's intelligent, generous, a beautiful person, and I hope to work with her again and again."
Jessica Chastain and Anne Hathaway at the Los Angeles premiere of Interstellar
Anne quickly thanked Jessica, before calling out to the reporter: "that's so funny, I knew when you picked me out when I was sitting next to Jessica that there had to be somewhere you were going with that, but thank you so very much for that [Jessica], it was so kind."
Oscar winner Anne has been the subject of memes and think-pieces on why she is not a likable actress, but Matthew McConaughey, who takes the lead role of Coop in Christopher Nolan's sci-fi epic also jumped to Anne's defence.
"It was my first time working with Anne, and I thoroughly enjoyed it", said Matthew.
Matthew McConaughey and Anne Hathaway in Interstellar
Anne admitted in 2013 that she knew about the "hatha-haters" and that she was often the butt of many jokes. In a recent interview she discussed how it made her feel.
"What are we supposed to do—pretend like it didn't happen?" she said.
"People treated me a certain way. But I've grown from it. This whole thing has made me a way more compassionate and loving person. And I don't feel sorry for myself. I was in crisis. Now I'd be fine. I really would be. I'd let it roll off my back, but at the time I was still partly Fantine. I was still identifying with being a victim."
Anne won her first Oscar in 2013 for Les Miserables, but revealed earlier in October that becoming famous messed her up "for a really long time."
"I didn't know how to do it; I didn't know how to engage with it; it stressed me out. And people would say, 'You just have to be yourself,' and I was like, 'But I don't know who that is yet!", she added.
Interstellar is out on 7 November