Rachel Weisz and US film director Darren Aronofsky have ended their nine-year relationship.
In a statement, the former couple confirmed that they had been "separated for some months".
They said that "they remain close friends" and "committed to raising their son together in New York City."
London-born Rachel and Darren - whose next film, Black Swan, has been tipped for Oscar glory - are parents to four-year-old Henry.
Darren, 41, proposed to the 40-year-old actress in Times Square after work finished on their 2006 collaboration The Fountain, but they never married.
The Constant Gardner beauty's boyfriends have included Neil Morrissey, Sam Mendes – ex-husband of Kate Winslet - and comedian Ben Miller.
US website TMZ is romantically linking her to Dream House co-star Daniel Craig, who has been with his girlfriend Satsuki Mitchell since 2005.
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