Chrissy Metz reveals the changes she's experienced since taking weight loss drugs


The This Is Us star opened up about the benefits of getting on a weight loss drug after years of trying different methods of losing weight


Chrissy Metz attends Apple's "Nocturne" New York Premiere at Regal Union Square on October 20, 2026 in New York City.© Getty Images
Beatriz Colon
Beatriz ColonNew York WriterNew York
1 hour ago

Chrissy Metz is happy to be on a GLP-1 — and get candid about it.

The This Is Us star, 45, has long been candid about her weight journey, which was even used as a plot line in the ABC drama.

Earlier this year, she revealed after years of trying different approaches to weight loss, she finally turned to the weight loss drug, and it has earned her a much deserved level of freedom.

 Chrissy Metz attends the New York premiere of Apple's "Nocturne" at Regal Union Square on October 20, 2026 in New York City. (Photo by Rob Kim/WireImage)© WireImage
Chrissy attending the premiere of Nocturne

Speaking with Entertainment Tonight, Chrissy shared that one of the best health benefits of being on a weight loss drug has been "being able to run around a stage," which she did for eight shows a week during her Broadway stint on &Juliet.

"The inflammation was really minimized," she said. "You know, I'm perimenopausal, I have knee issues. There are things going on."

"I think also the mental capacity to have other things to think about than obsessing about the food noise and all that, that's been super helpful," she added.

Chrissy Metz attends the 2021 InStyle Awards at The Getty Center on November 15, 2021 in Los Angeles, California. (Photo by Emma McIntyre/Getty Images for InStyle)© Getty Images
The actress is now an ambassador for Ro

Chrissy, who stars in the forthcoming AppleTV crime drama Nocturne, also starring Steohen Graham, Liev Schreiber, and Zazie Beetz, among others, previously told People about getting on Ro: "I'm in perimenopause, and there were obesity issues within my family and with my father, and I felt like I've tried so many modalities, whether it was diets or therapy, and none of it really worked for me."

Recommended videoYou may also likeWATCH: Chrissy Metz opens up about her imposter syndrome on TODAY with Jenna & Sheinelle

Maintaining it's been a "great" experience, she said: "I've enjoyed the benefits that I didn't think would come, because I was very skeptical."

"I was like, 'I'm not taking this medication. I don't wanna do this. It's not gonna work for me.' You know, all the things," she recalled. "But when I realized food noise was really a thing, that consumed a lot of my head space, I was like, 'Oh.'"

Chrissy sitting alongside Justin Hartley for a scene in This Is Us© Getty Images
Her weight loss journey was part of a plot line on This Is Us

"It's so nice not to be obsessing about what I'm going to have every minute, even as I'm still consuming the meal," she continued, detailing just some of the benefits of the medication. "I just vilified food for so long because I was taught that it was bad, and you shouldn't eat this or that."

 Chrissy Metz as "Angelique" and Olympic Gold medalist Laurie Hernandez as "Charmion" pose during a celebration for the hit musical comedy "& Juliet" as it welcomes Chrissy Metz to the cast and marks 1500 performances on Broadway at The Stephen Sondheim Theatre on June 23, 2026 in New York City© Getty Images
She recently ended a run on &Juliet

Chrissy also addressed the criticism she might face, teasing when it comes to her, "everybody is judgy," but maintaining it "doesn't matter," because people will judge her for not being on a GLP-1 just as they will for being on one.

"I always say, they're not in my life. They're not in my doctor's notes. They're not in the hereditary issues my family has. My life is my life, and I have to do what's best for me, and that includes not listening to the comments and just talking to people who are positive and kind. I can't engage with something that doesn't make me feel good," she emphasized. 

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