Speaking exclusively to the magazine, she insists that it's hard for her to meet men due to her unsocial working hours as co-host of Capital FM.
"I don’t go anywhere," she said. "I go to the supermarket. I go to work. So there aren't many opportunities to meet people.
"Unless you're kind of bonding over the deli counter, it’s not going to happen."
Her ex-boyfriend, George Clooney, also recently became single again, and a bookmaker has offered odds on them getting back together.
"We're friends," she said. "I got back with George a couple of times, and have also got back with other exes, because sometimes I've felt like it's a safer place to go.
"But you do have to realise you split for a reason."
She's not sure he will marry again. "I can't really speak on his behalf," she says.
"But my feeling is that he did get married, he did try it and it didn't work, so maybe he won't do it again."
Lisa, in turn, is happy with her "very single" status. "I don't feel like my life is incomplete," she says.
"I don't feel like a man defines who I am. I'm not lonely. I have great friends and I'm really close to my family."
Lisa, who turns 40 in January, adds: "I love children but I'm not sure that's for me anymore."
She says that her recent holiday on the island of Parrot Cay, where Bruce Willis and Christie Brinkely own homes, was rejuventating.
"I have never felt as good as when I was in Parrot Cay," she said.
Modelling a swimsuit and bikini in the exclusive HELLO! photoshoot, she says that her enviable figure is "due to maintenance" as she follows a healthy diet and goes to the gym three times a week.
When asked about her views on Botox and cosmetic surgery, she says. "I'm not quite ready to do it but never say never."
SEE THE FULL EXCLUSIVE ARTICLE IN HELLO! MAGAZINE,OUT NOW.