The collection of work explores the painter El Greco and his influence on modern greats such as Francis Bacon and Jackson Pollock.
Letizia arrives for her first solo engagement as queen
A former journalist, Letizia has reported from some of the world's most hostile environments, including the frontlines of the Iraq War, and has dealt with delicate stories such as the September 11 attacks.
Now one of Europe's most fashionable royals, Letizia looked stylish and elegant in a pale floral dress with a belt at the waist as arrived at the Prado - which is one of the country's top art musuems.
Last Thursday, Letizia proudly watched her husband officially accede the throne with the couple's two daughters Princess Sofia and Princess Leonor. Felipe became king of Spain on the stroke of midnight on Wednesday, following the abdication of his father, King Juan Carlos.
Queen Letizia of Spain
Despite the importance and formality of the ceremony, it remained a touching family affair.
The king's first act was to officially receive the red sash of the chief of the Armed Forces from his father. The two men then embraced as their family applauded. Felipe, dressed in his blue military uniform, walked over to his loved ones, including his mother Queen Sofia, and kissed them all, while Juan Carlos shook hands with officials.