During a joint appearance on Tuesday's Lorraine, the famous singers - aged 61 and 69 respectively - confessed their battle amid the pandemic has made their fight even harder.
Linda's illness is incurable but treatable, she was diagnosed with secondary cancer in her liver. Anne, on the other hand, has breast cancer and was diagnosed back in April. The star is now waiting to see if her latest round of chemotherapy has worked.
"I've had my chemo, it's gone according to plan," she explained. "I'm just waiting for the results of scans that I’ve had to see if the chemo has worked."
WATCH: Linda Nolan emotionally rings the chemo bell in hospital
Speaking of the loss of their sister Bernie to cancer, Linda said: "I once remember Bernie saying - we miss her every minute of every day - I do remember someone saying to Bernie, 'Your poor family'. She said, 'I've never said why me. Why not me?'
"Three sisters having breast cancer, we've had the gene test, we don't have the BRCA1 or 2, there will be a rogue gene somewhere that we've got, they haven't found it yet."
She added: "Bernie was a warrior. You'd say, 'Do you want some water?' and she'd say, 'No, I want some vodka and ginger ale.'"
The sisters appeared on Tuesday's Lorraine to give fans an update
Anne finished her chemotherapy treatment in August and was discharged from Blackpool Victoria Hospital. Of going through treatment during the pandemic, she said: "I suffered really badly with anxiety, I think it's because of the Covid thing as well. Going through it in a pandemic when you can't have family around...
"[Last time] I was able to go out, have a good time. But you just have to take every day as it comes and be positive about the treatment that you’re having, even though it’s harsh and makes you ill, it’s to make you better. That’s the way to think about it. Whatever you’re going through is to make you better and to cure your cancer.
The sisters formed part of Irish pop group The Nolans (Linda pictured far left)
"My prognosis is very good at the moment. I had an operation about two weeks ago, the results were fabulous. They found no cancer in any of the tissue that they took from the breast and from my lymph nodes, and that was absolutely amazing. And that was because of the chemotherapy. The results were fantastic."
The pair then went on to urge viewers to get checked if they see any warning signs, with Linda saying: "Please don't wait. Don’t be frightened. The longer you wait your treatment might be worse. Make an appointment and get in there. I have never not felt safe [in hospital during the pandemic]."
Anne added: "Cancer doesn't wait. If you have a lump, go and get it checked. If it's cancer, it's not going to go away. If it's not cancer, the doctor will tell you and you'll feel relieved."
Make sure you never miss a story! Sign up to our newsletter to get all of our celebrity, royal and lifestyle news delivered directly to your inbox.