In honor of the beloved variety series' 50th anniversary, the "Manchild" pop-star along with Disney and Seth Rogen came together to create a one night only special, bringing back the likes of Kermit the Frog and Miss Piggy, among others.
It premieres tonight, February 4, at 9pm ET on ABC, though is available now for Disney+ subscribers.
In addition to your favorite Muppets, Sabrina and Seth are both making appearances in the 33-minute special, as is beloved comedian Maya Rudolph.
In honor of the anniversary, and the sweet special, take a look back at some of The Muppets Show's best celebrity cameos, and see who voiced the kooky characters originally.
Kermit was created in 1955, and originally performed by his creator Jim Henson, who was 19 years old when he created Kermit. He passed away aged 53 in 1990 from organ failure due to streptococcal toxic shock syndrome (STSS) caused by a Group A streptococcus infection. Kermit, pictured above with Lady Gaga in 2009, has been voiced by Matt Vogel since 2009.
Miss Piggy, pictured above with fellow icon Julie Andrews in 1977, was created and originally voiced by Fran Oz, primary puppeteer for Jim, until 2002.
Pepé The King Prawn, Gonzo, Fozzie Bear & Robert De Niro
Pepé, now voiced by Bill Barretta, Gonzo, now voiced by Dave Goelz, and Fozzie Bear, now also voiced by Eric, with the Taxi Driver actor at the TriBeCa Film Festival in 2005.
The Landman actress, who stars in the Billy Bob Thornton-led show as Angela, gave insight into what the Yellowstone mastermind is like as a show creator
The latest episode of the Nathan Fillion led show brought back Patrick Keleher as the conniving Seth Ridley, who fans had last seen at the end of season seven