One of Hollywood's high profile couples have gone their separate ways.
According to sources, Renee Zellweger and Bradley Cooper have called time on their relationship after nearly two years together.
Reps for the pair have refused to comment.
Renee, 41, and the Hangover actor first met on the set of Case 39 six years ago. But romance didn’t blossom until the summer of 2009.
The couple never officially confirmed their relationship, but they were frequently seen in each other's company and moved in together in September 2010.
Speaking in an interview last year, the 36-year-old actor praised his Case 39 co-star, saying: "I can't say enough about her.
"I just love her. I (loved) coming to work. I love acting with her. I can learn so much from her."
In January, Renee skipped the Golden Globes to be with Bradley following the death of his father. She was also particularly close to his mother Gloria.
Previous News In Pictures: