Meet Conan O'Brien's five siblings – including sister who starred in Academy Award winning film


Several of the beloved late night TV host's siblings have gone into showbiz – meet his five siblings, from film stars to lawyers


NEW YORK, NEW YORK - FEBRUARY 16: Conan O'Brien attends SNL50: The Anniversary Special on February 16, 2025 at 30 Rockefeller Center in New York City. (Photo by Taylor Hill/FilmMagic)© FilmMagic
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Late night television wouldn’t be the dependable network hit it is without hosts like Conan O’Brien. After three and a half seasons on SNL and a three year stint as a writer and producer on The Simpsons, Conan headed for the bright lights of TV chat shows. Late Night with Conan O’Brien ran on NBC between 1993 and 2009 for an impressive 2725 episodes total, giving the host a chance to squeeze in a brief stint on The Tonight Show, before heading off for the self-titled chat show Conan on TBS.  

Now, the 62-year-old heads up his regular podcast Conan O’Brien Needs a Friend, and travel show Conan O’Brien Must Go where he surprises fans across the globe. It’s no wonder he’s made a name for himself as a talkative joker – one of six siblings, some of which have also found success in the spotlight or on the studio floor, Conan is certainly capable of rising above the noise. We’re taking a look at the lives of those who know the comedian best, from start-up aficionados to movie stars.

JIMMY KIMMEL LIVE!  "Jimmy Kimmel Live!" airs every weeknight at 11:35 p.m. ET and features a diverse lineup of guests that include celebrities, athletes, musical acts, comedians and human interest subjects, along with comedy bits and a house band. The guests for Tuesday, February 25 included Conan O'Brien ("The Oscars®") and Regé-Jean Page ("Black Bag"). (Disney/Randy Holmes)
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Conan is one of the biggest names in late night TV

Neal O’Brien (1960)

The eldest of Conan’s siblings, Neal largely avoids the spotlight. Reportedly now working as an antique car collector, Conan’s big brother lives in the O’Brien siblings’ hometown of Brookline, Massachusetts. Speaking to Michele Norris on the Your Mama’s Kitchen podcast, Conan recalled how his mother excitedly gave Neal a tour of her office upon her return to full-time legal work. 

“She took Neal downtown to the State Street Bank building, got in the elevator and showed her office to Neal, which was, I think, a modest office when she first went back. Then she worked her way up to partner and she got a corner office,” he recalls. “Neal said it was like a kid showing you his new bike. She was so proud that she had her office in the law firm, and Neal remembers that very well.”

Luke O’Brien (1961)

LAWRENCE, MA - SEPTEMBER 25: Labels Are For Jars (LAFJ) and Cor Unum announced today the successful completion of the Cor Unum Meal Center, a 5,600 square foot facility that will help feed hungry families in Lawrence starting Sept. 30. LAFJ member Conan O'Brien, left, and his brother, Luke, right, of Watertown, Mass., joined other leaders to break bread in support of the meal center they helped make possible. (Photo by Janet Knott/The Boston Globe via Getty Images)© Boston Globe via Getty Images
Conan and his brother Luke together in 2006

Luke followed in his mother’s footsteps, and works as a principal at Trinity Law Group. Luke also studied a bachelor’s in biology at the College of the Holy Cross before gaining his law degree from Suffolk University Law School. Speaking to the school, Luke reflected on his decision to leave a consultancy role for a start-up position. “I’ve done four now. I love it, I wouldn’t change it for the world,” he said. “It’s gruelling, it’s an intense amount of work but it’s immensely rewarding.” Luke lives in Massachusetts with his wife Ilse. 

Kate B. O’Brien (1965)

Actresses Actresses (L-R) Kate B. O'Brien, Bianca Hunter, Jenna Lamia, Melissa McMeekin, Erica McDermott and Dendrie Taylor arrives at the 2011 MTV Movie Awards at Universal Studios' Gibson Amphitheatre on June 5, 2011 in Universal City, California. (Photo by Steve Granitz/WireImage)© WireImage
Kate (far left) is an actress

Kate, like Conan and their sister Jane, opted instead for a path in Hollywood. She has worked alongside the likes of Amy Adams, Christian Bale and Mark Wahlberg in The Fighter (2010. Kate cameoed as Micky (Wahlberg) and Dicky’s (Bale) sister Phyllis Eklund. The film explores an Irish Catholic  family’s pursuit of fame in the world of boxing, a role which seemed to come naturally.

The actress explained to People Magazine, “I’m one of six, so it wasn’t that hard for me to look like I might have more siblings.” The actress has also appeared in Ted 2 (2015) as a diner waitress and in an episode of The Expecting (2020) as an alien witness. She lives in Boston, Massachusetts.

Jane C. O’Brien (1967)

Unlike her other showbiz siblings, Jane seems more at home behind the screen than in front of it and as such has an extensive list of written and production credits to her name. From American sitcom Cybill, for which she penned seven episodes, to The Simpsons, where she story edited 22 episodes and penned one herself. 

Jane has had a hand in some iconic programming. Other credits include producing 20 episodes of Futurama between 1999-2000, writing an episode of Battery Park in 2000 and producing seven episodes of Costello in 1998. Unlike most of the O’Brien clan, the producer lives outside of Massachusetts in sunny San Anselmo, California. 

OSLO, NORWAY-DECEMBER 11: Conan O'Brien  speaks to the audience and celebrate this yearâs Nobel Peace Prize laureate President Juan Manuel Santos of Colombia, during the Nobel Peace Prize Concert at Telenor Arena on December 11, 2016 in Oslo, Norway. (Photo by Nigel Waldron/ Getty Images)© Getty Images
Conan's sister Jane is an expert behind the scenes

Justin O’Brien (1972)

Like his older brother Luke, Justin followed in his mother’s footsteps into law. Conan’s eldest sibling graduated with his bachelor’s degree in history from Harvard Law School and his law degree from Boston College Law School. Justin went on to found Lovett O’Brien in Boston, where he works as a partner. Before finding success in the legal sector, he pursued a career in politics, campaigning for US senators Edward Kennedy and John Kerry and working as a deputy director of the Massachusetts Democratic Party. He lives in Massachusetts with his wife Joanna.

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