And some of her great-grandchildren share a special connection with Her Majesty and her late husband, the Duke of Edinburgh.
Princess Beatrice and Edoardo Mapelli Mozzi revealed their daughter's full name almost two weeks after her birth, calling her Sienna Elizabeth Mapelli Mozzi, in a sweet nod to the Queen.
WATCH: The next generation of young royals
The couple's second child is Lena Elizabeth Tindall and her middle name pays homage to the Queen.
Eugenie and Jack with their baby son August
Royal cousins Lena Tindall and Isla Phillips have the middle name Elizabeth
And it's not just the Queen's great-grandchildren who share a special connection – every couple in the monarch's immediate family has chosen to give one of their children the middle name Elizabeth.
Princess Anne's full name is Anne Elizabeth Alice Louise, while her daughter is Zara Anne Elizabeth Tindall.
Prince Andrew and Sarah, Duchess of York's firstborn daughter is Princess Beatrice Elizabeth Mary. Likewise, Prince Edward and the Countess of Wessex's daughter is Lady Louise Alice Elizabeth Mary Mountbatten-Windsor.
When it comes to welcoming the next generations of the family in future, you can almost guarantee that one of them will have the middle name Elizabeth.
Make sure you never miss a ROYAL story! Sign up to our newsletter to get all of our celebrity, royal and lifestyle news delivered directly to your inbox.